Problems Faced by Pharma

In today’s market for pharmaceuticals, drugs that follow traditional design principles continue to fail at the critical step of clinical trials due to toxicity. In many cases, this can be attributed to non-specific interactions in the body.  However, even if a drug does complete clinical trials, its indication for usage is often adjusted to limit risks associated with these same safety concerns and to minimize downstream implications for future liability. 

At present, the following represent key challenges that have an unmet need in the drug delivery industry:

  • Poor solubility
  • Systemic drug toxicity
  • Immune response
  • Drug accumulation and poor elimination
  • Poor circulation times and half-life
  • Patent protection